FITC标记的11号染色体开放阅读框57抗体
产品名称： FITC标记的11号染色体开放阅读框57抗体
英文名称： Anti-C11orf57/FITC
产品编号： HZ-9939R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-C11orf57/FITC Conjugated antibody
FITC标记的11号染色体开放阅读框57抗体
| 产品编号 | bs-9939R-FITC |
| 英文名称 | Anti-C11orf57/FITC |
| 中文名称 | FITC标记的11号染色体开放阅读框57抗体 |
| 别 名 | chromosome 11 open reading frame 57; CK057_HUMAN; FLJ10726; hypothetical protein LOC55216; Uncharacterized protein C11orf57. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C11orf57 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: C11orf57, also known as FLJ10726, is a 292 amino acid protein that exists as three alternatively spliced isoforms and is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. Database links: Entrez Gene: 55216 Human SwissProt: Q6ZUT1 Human Unigene: 195060 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
C11ORF57，也称为FLJ10726，是一种292个氨基酸的蛋白质，以三个交替剪接的亚型存在，并由位于人类染色体11上的基因编码。大约有1亿3500万个碱基对和1400个基因，染色体11构成了人类基因组DNA的4%，被认为是一个基因和疾病相关的密集染色体。11号染色体编码ATM基因是调控双链DNA断裂后细胞周期阻滞和凋亡的重要因素。ATM突变导致称为共济失调毛细血管扩张症。血液病镰状细胞贫血和β地中海贫血是由HBB基因突变引起的。WLMS肿瘤、WAGR综合征和Duny-Drasy综合征与WT1基因突变有关。Jurvl和Lange Nielsen综合征、杰克布森综合征、尼曼匹克病、遗传性血管水肿和Smith-LeMi-Opz综合征也与11号染色体上的缺陷有关。