FITC标记的α2纤溶酶色素上皮衍生因子抗体
产品名称： FITC标记的α2纤溶酶色素上皮衍生因子抗体
英文名称： Anti-Alpha 2 antiplasmin /FITC
产品编号： HZ-6188R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-Alpha 2 antiplasmin /FITC Conjugated antibody
FITC标记的α2纤溶酶色素上皮衍生因子抗体
| 英文名称 | Anti-Alpha 2 antiplasmin /FITC |
| 中文名称 | FITC标记的α2纤溶酶色素上皮衍生因子抗体 |
| 别 名 | A2AP; A2AP_HUMAN; AAP; Alpha 2 antiplasmin; Alpha 2 antiplasmin pigment epithelium derived factor; Alpha 2 AP; ALPHA 2 PI; Alpha 2 plasmin inhibitor; Alpha 2 plasmin inhibitor deficiency; Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-PI; Alpha-2-plasmin inhibitor; Antiplasmin deficiency; API; Plasmin inhibitor deficiency; PLI; Serine (or cysteine) peptidase inhibitor, clade F, member 2; Serine (Or cysteine) peptidase inhibitor, clade F, member 2, isoform CRA_c; Serine (or cysteine) proteinase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2; Serine (Or cysteine) proteinase inhibitor, clade F, member 2; Serine or cysteine peptidase inhibitor clade F member 2; Serpin F2; Serpin peptidase inhibitor clade F; Serpin peptidase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2; SERPINF2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 免疫学 泛素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 50kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SERPINF2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Alpha 2 Antiplasmin is a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. Function: Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. Subunit: Forms protease inhibiting heterodimer with TMPRSS7. Subcellular Location: Secreted. Tissue Specificity: Expressed by the liver and secreted in plasma. DISEASE: Alpha-2-plasmin inhibitor deficiency (APLID) [MIM:262850]: An autosomal recessive disorder resulting in severe hemorrhagic diathesis. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the serpin family. Database links: UniProtKB/Swiss-Prot: P08697.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
α2抗纤溶酶是丝氨酸蛋白酶抑制剂Serppin家族的成员。蛋白质是纤溶酶的主要抑制剂，它降解纤维蛋白和各种其他蛋白质。因此，该基因的适当功能在调节凝血通路中具有重要作用。该基因的突变导致α-2纤溶酶抑制剂缺乏，其特征是严重的出血性素质。该基因已发现编码不同亚型的多个转录变体。