Anti-Nav1.1 mAb: ATTO 488 [S74-71]-抗体-抗体-生物在线
StressMarq
Anti-Nav1.1 mAb: ATTO 488 [S74-71]

Anti-Nav1.1 mAb: ATTO 488 [S74-71]

商家询价

产品名称： Anti-Nav1.1 mAb: ATTO 488 [S74-71]

英文名称： Nav1.1 Monoclonal Antibody: ATTO 488 [S74-71]

产品编号： SMC-376D-A488

产品价格： null

产品产地： 加拿大

品牌商标： StressMarq

更新时间： null

使用范围： WB, IHC, IP

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Voltage gated sodium channels initiate action potentials in neurons. Nav1.1 is abundant in the adult brain, and
primarily localized in cell bodies. Mutations in the Nav1.1
channels cause generalized epilepsy with febrile seizures
plus (GEFS+). Studies show that Nav1.1 channels also play a
crucial role in the excitability of cerebellar Purkinje
neurons, with major contributions to peak, persistent and
resurgent forms of sodium current and to sustained action
potential firing (3).