MUTYH抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
MUTYH抗体

MUTYH抗体

商家询价

产品名称： MUTYH抗体

英文名称： MUTYHAntibody

产品编号： XY15237-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 MUTYH抗体

Applications
In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 15237-1-AP;K-562 cellK-562 cells were subjected to SDS PAGE followed by western blot with 15237-1-AP(MUTYH antibody) at dilution of 1:300
Positive WB detected in K-562 cells, HeLa cells, Raji cells
Recommended dilution WB : 1:200-1:2000
 MUTYH抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen MUTYH fusion protein ag7359 Full name MutY homolog (E. coli)
Calculated molecular
weight		 60 kDa Observed molecular 
weight		 53kd,65kd
GenBank accession 
number		 BC003178 Gene ID (NCBI) 4595
Gene symbol MUTYH Synonyms HMYH, MutY homolog, mutY homolog (E. coli), MUTYH, MYH
Background MUTYH抗体

MUTYH(MutY homolog) is also named as MYH and belongs to the Nth/MutY family. The gene enconde an A/G-specific adenine DNA glycosylase that it is involved in oxidative DNA damage repair and initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities(PMID:10684930). Defects in MUTYH are a cause of familial adenomatous polyposis type 2 (FAP2) and gastric cancer (GASC). It has 6 isoforms produced by alternative splicing with the molecular weight between 57 kDa and 60 kDa. MUTYH抗体

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